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shossain@ru.ac.bd

Dept. of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh.


MD. SHAKHAWOAT HOSSAIN
PROFESSOR
Biochemistry & Molecular Biology


Education Summary  
PhD, TMDU, Japan

Research Interest  
Environmental Health, Toxicology, Molecular Biology, Cell Biology, Cancer Biology
Level Institution Year
Doctoral
(PhD)
Tokyo Medical and Dental University 2019
Masters
(Masters of Science)
University of Rajshahi 2005
Bachelor/Honors
(Bachelor of Science)
University of Rajshahi 2004

Experience in Rajshahi University

Duration Organization/Institute Position
2024-10-12 to Department of Biochemistry and Molecular Biology PROFESSOR
2019-06-27 to 2024-10-11 Department of Biochemistry & Molecular Biology ASSOCIATE PROFESSOR
2013-01-02 to 2019-06-26 Department of Biochemistry & Molecular Biology ASSISTANT PROFESSOR
2010-01-02 to 2013-01-01 Department of Biochemistry & Molecular Biology LECTURER

Experience in other Organization/Institute

Duration Organization/Institute Position
2008-08-12 to 2010-01-01 Renata PLC Quality Assurance Officer

Journal

1. Asma Ul Husna Biswas, Tasnima Kamal, Azmin Akter, Sharmin Akter, Azadur Rahman Bhuiyan, Zinnat Ara Moni, Abdul Auwal, Nitai Roy, Shakhawoat Hossain, Farhadul Islam "Antioxidant and Hepatotoxicity Ameliorative Potential of Mentha canadensis Leaves Against Paracetamol‐Induced Hepatic Damage in Mice" Food Science & Nutrition;13(12), e71279

Published: December 2025
2. Kamrun Nahar Rossi, Faysal Abedin, Nayan Chandra Mohanto, Biplob Ahmed, Sobuj Mia, Nesar Uddin, Rajoana Karim Rimi, Osman Goni, Sharon Jahan Sarder, Sajib Hossain, Mainul Islam, Ahsanul Mahbub Jubayar, Md Shofikul Islam, Shakhawoat Hossain, Md Ashraful Ho "Ghrelin-disrupting activity of arsenic and its relation to cardiometabolic diseases" Toxicology and Applied Pharmacology;117676

Published: December 2025
3. Osman Goni, Nesar Uddin, Rajoana Karim Rimi, Kamrun Nahar Rossi, Faysal Abedin, Sharmin Akter Beauty, Sharon Jahan Sarder, Junayed Sadi, Mainul Islam, Victor Mondal, KM Kabir, Abu Eabrahim Siddique, Shakhawoat Hossain, Md Ashraful Hoque, Tetsuro Agusa, Da "Association between Arsenic Exposure and CCL5: its Implications in Asthma and Skin Lesions" Exposure and Health; 18(1), 7

Published: December 2025
4. Sharmin Akter Beauty, Sharon Jahan Sarder, Jakir Hossain, Nesar Uddin, Osman Goni, Rajoana Karim Rimi, Shakhawoat Hossain, Farjana Nikkon, Seiichiro Himeno, Khaled Hossain, Zahangir Alam Saud "Regular Exercise with Panax Ginseng Supplementation Attenuates Arsenic-Induced Muscular Weakness and Neurobehavioral Changes in Mice" Neurotoxicity Research, 45(5):1-15

Published: October 2025
5. Ahsanul Mahbub Jubayar, Shuchismita Khan, Junayed Sadi, Nesar Uddin, Osman Goni, Moriom Khatun, Abu Eabrahim Siddique, Ehsanul Kabir, Rajoana Karim Rimi, Sharmin Akter Beauty, Kamrun Nahar Rossi, Faysal Abedin, Sharon Jahan Sarder, Md Shofikul Islam, Md K "Novel evidence of arsenic-related excess adiposity and its implication in the risk of cardiometabolic diseases" Environmental Research, 271,121059

Published: April 2025
6. Ehsanul Kabir, Tasnim Tabassum Shila, Jahidul Islam, Sharmin Akter Beauty, Farhadul Islam, Shakhawoat Hossain, Farjana Nikkon, Seiichiro Himeno, Khaled Hossain & Zahangir Alam Saud "Concomitant Exposure to Lower Doses of Arsenic, Lead, and Manganese Induces Greater Synergistic Neurotoxicity Than Individual Metals in Mice" Biological Trace Element Research

Published: June 2024
7. Ehsanul Kabir, Jahidul Islam, Tasnim Tabassum Shila, Sharmin Akter Beauty, Junayed Sadi, Md Royhan Gofur, Farhadul Islam, Shakhawoat Hossain, Farjana Nikkon, Khaled Hossain, Zahangir Alam Saud "Ameliorating effects of Clerodendrum viscosum leaves on lead‐induced hepatotoxicity" Food Sci Nutr. 2024;00:1–10

Published: June 2024
8. Moriom Khatun, Nazmul Haque, Abu Eabrahim Siddique, Abdus S Wahed, Md Shofikul Islam, Shuchismita Khan, Ahsanul Mahbub Jubayar, Junayed Sadi, Ehsanul Kabir, Tasnim Tabassum Shila, Zohurul Islam, Md Khalequzzaman Sarker, Hasan Ul Banna, Shakhawoat Hossain, "Arsenic Exposure-Related Hypertension in Bangladesh and Reduced Circulating Nitric Oxide Bioavailability" Environmental Health Perspectives;132(4), 047003

Published: April 2024
9. Jahidul Islam 1, Zohurul Islam 1, Nazmul Haque, Moriom Khatun, Farhadul Islam, Shakhawoat Hossain, Md Ashraful Hoque, Farjana Nikkon, Khaled Hossain, Zahangir Alam Saud "Fenugreek seed powder protects mice against arsenic-induced neurobehavioral changes" Current Research in Toxicology 5 (2023) 100114

Published: July 2023
10. Moriom Khatun, Abu Eabrahim Siddique, Abdus S Wahed, Nazmul Haque, Selim Reza Tony, Jahidul Islam, Shahnur Alam, Md Khalequzzaman Sarker, Isabela Kabir, Shakhawoat Hossain, Daigo Sumi, Zahangir Alam Saud, Aaron Barchowsky, Seiichiro Himeno, Khaled Hossain "Association between serum periostin levels and the severity of arsenic-induced skin lesions" PLoS ONE 18(1): e0279893. https://doi.org/10.1371/journal.pone.0279893

Published: January 2023
11. Zohurul Islam, Jahidul Islam, Selim Reza Tony, Adiba Anjum, Rafia Ferdous, Apurba Kumar Roy, Shakhawoat Hossain, Kazi Abdus Salam, Farjana Nikkon, Khaled Hossain, Zahangir Alam Saud "Mulberry leaves juice attenuates arsenic-induced neurobehavioral and hepatic disorders in mice" Food Sci Nutr. 2022;10:4360–4370. DOI: 10.1002/fsn3.3028

Published: August 2022
12. Selim Reza Tony , Nazmul Haque , Abu Eabrahim Siddique , Moriom Khatun, Mizanur Rahman, Zohurul Islam, Md Shofikul Islam, Jahidul Islam, Shakhawoat Hossain , Md Ashraful Hoque , Zahangir Alam Saud , Daigo Sumi , "Elevated serum periostin levels among arsenic-exposed individuals and their associations with the features of asthma" Chemosphere,298, 134277. https://doi.org/10.1016/j.chemosphere.2022.134277

Published: July 2022
13. Joshua Agbemefa Kuleape, Shakhawoat Hossain, Caleb Kwame Sinclear, Takanobu Shimizu, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Hiroshi Nishina, Yutaka Hata "DNA damage triggers the nuclear accumulation of RASSF6 tumor suppressor protein via CDK9 and BAF53 to regulate p53-target gene transcription" Mol Cell Biol. 2022 Feb 17;42(2):e0031021. doi: 10.1128/MCB.00310-21. Epub 2021 Dec 13.

Published: February 2022
14. Md. Khalequzzaman Sarker, Selim Reza Tony, Abu Eabrahim Siddique, Nazmul Haque, Md. Shofikul Islam, Faruk Hossain, Zohurul Islam, Shakhawoat Hossain, Md Ashraful Hoque, Zahangir Alam Saud, Daigo Sumi, Seiichiro Himeno & Khaled Hossain "Gender Differences in the Risk of Metabolic Syndrome Among Chronic Arsenic-Exposed Individuals in Bangladesh" Exposure and Health (2021), https://doi.org/10.1007/s12403-021-00437-1

Published: October 2021
15. Md. Khalequzzaman Sarker,Selim Reza Tony, Abu Eabrahim Siddique, Md. Rezaul Karim, Nazmul Haque, Zohurul Islam, Md. Shofikul Islam, Moriom Khatun, Jahidul Islam, Shakhawoat Hossain, Zahangir Alam Saud, Hideki Miyataka, Daigo Sumi, Aaron Barchowsky, Seiich "Arsenic Secondary Methylation Capacity Is Inversely Associated with Arsenic Exposure-Related Muscle Mass Reduction" Int. J. Environ. Res. Public Health 2021, 18(18), 9730

Published: September 2021
16. Atiqur Rahman, Md. Shofikul Islam, Selim Reza Tony, Abu Eabrahim Siddique, Victor Mondal, Zubaer Hosen, Zohurul Islam, Md. Imam Hossain, Mizanur Rahman, Adiba Anjum, Sudip Kumar Paul, Faruk Hossen, Md. Khalequzzaman Sarker, Shakhawoat Hossain, Kazi Abdus "T helper 2-driven immune dysfunction in chronic arsenic-exposed individuals and its link to the features of allergic asthma" Toxicol Appl Pharmacol. 2021 Jun 1;420:115532. doi: 10.1016/j.taap.2021.115532. Epub 2021 Apr 13.

Published: June 2021
17. Victor Mondala, Zubaer Hosenb, Faruk Hossena, Abu Eabrahim Siddique, Selim Reza Tony, Zohurul Islam, Md.Shofikul Islam, Shakhawoat Hossain, Khairul Islam, Md. Khalequzzaman Sarker, M.M.Hasibuzzaman, Ling-Zhi Liu, Bing-Hua Jiang, Md Mominul Hoque, Zahangir "Arsenic exposure-related hyperglycemia is linked to insulin resistance with concomitant reduction of skeletal muscle mass" Environ Int. 2020 Oct;143:105890. doi: 10.1016/j.envint.2020.105890. Epub 2020 Jun 30.

Published: October 2020
18. Hossain S, Iwasa H, Sarkar A, Maruyama J, Arimoto-Matsuzaki K, Hata Y "The RASSF6 Tumor Suppressor Protein Regulates Apoptosis and Cell Cycle Progression via Retinoblastoma Protein" Mol Cell Biol. 38: e00046-18 e00046-18.

Published: June 2018
19. Iwasa H, Sarkar A, Shimizu T, Sawada T, Hossain S, Xu X, Maruyama J, Arimoto-Matsuzaki K, Withanage K, Nakagawa K, Kurihara H, Kuroyanagi H, Hata Y "UNC119 is a binding partner of tumor suppressor Ras-association domain family 6 and induces apoptosis and cell cycle arrest by MDM2 and p53" Cancer Science,109:2767–2780.

Published: June 2018
20. Iwasa H, Hossain S, Hata Y "Tumor suppressor C‑RASSF proteins" Cell Mol Life Sci. ,75:1773-1787

Published: May 2018
21. Xu X, Iwasa H, Hossain S, Sarkar A, Maruyama J, Arimoto-Matsuzaki K, Hata Y "BCL-XL binds and antagonizes RASSF6 tumor suppressor to suppress p53 expression" Genes to Cells. 22:993-1003

Published: October 2017
22. Hossain S, Hasibuzzaman MM, Islam MS, Rahman A, Anjum A, Hossain F, Mohanto NC,Karim MR, Hoque MM, Saud ZA, Miyataka H3, Himeno S, Hossain K "Association between arsenic exposure and soluble thrombomodulin: A cross sectional study in Bangladesh" PloS One.12(4): e0175154

Published: April 2017
23. K, Suzuki T, Hasibuzzaman MM, Islam MS, Rahman A, Paul SK, Tanu T, Hossain S, Saud ZA, Rahman M, Nikkon F, Miyataka H, Himeno S, Nohara K "Chronic exposure to arsenic, LINE-1 hypomethylation, and blood pressure: A cross-sectional study in Bangladesh" Environmental Health 16:20

Published: March 2017
24. A, Iwasa H, Hossain S, Xu X, Sawada T, Shimizu T, Maruyama J, Arimoto-Matsuzaki K, Hata Y "Domain analysis of Ras-association domain family member 6 upon interaction with MDM2" FEBS Letters. 591:260-272

Published: January 2017
25. Rahman M, Al Mamun A, Karim MR, Islam K, Al Amin H, Hossain S, Hossain MI, Saud ZA, Noman AS, Miyataka H, Himeno S, Hossain K "Associations of total arsenic in drinking water, hair and nails with serum vascular endothelial growth factor in arsenic-endemic individuals in Bangladesh" Chemosphere.120:336-42

Published: February 2015
26. Hossain S, Huda N, Rahman M, Karim MR, Islam K, Mamun AA, Hossain MI, Mohanto NC, Alam S, Aktar S, Arefin A, Ali N, Salam KA, Aziz A, Saud ZA, Miyataka H, Himeno S, Hossain K "Elevated levels of plasma uric acid and its relation to hypertension in arsenic-endemic human individuals in Bangladesh" Toxicology and Applied Pharmacology. 281(1) :11–18

Published: November 2014
27. Sheikh A, Yeasmin F, Agarwal 1, Rahman M, Islam K, Hossain E, Hossain S, Karim MR, Nikkon F, Saud ZA, Hossain K "Protective effects of Moringa oleifera Lam. leaves against arsenic-induced toxicity in mice" Asian Pac J Trop Biomed. 4(Suppl 1): S353-S358

Published: May 2014
28. Karim MR, Rahman M, Islam K, Mamun AA, Hossain S, Hossain E, Aziz A, Yeasmin F, Agarwal S, Hossain MI, Saud ZA, Nikkon F, Hossain M, Mandal A, Jenkins RO, Haris PI, Miyataka H, Himeno S, Hossain K "Increases in oxildized low density lipoprotein and other inflammatory and adhesion molecules with a concomitant decrease in high density lipoprotein in the individuals exposed to arsenic in Bangladesh" Toxicological Sciences. 135(1):17-25

Published: September 2013
29. Hossain E, Islam K, Yeasmin F, Karim MR, Rahman M, Agarwal S, Hossain S, Aziz A, Al Mamun A, Sheikh A, Haque A, Hossain MT, Hossain M, Haris PI, Ikemura N, Inoue K, Miyataka H, Himeno S, Hossain K "Elevated levels of plasma Big endothelin-1 and its relation to hypertension and skin lesions in individuals exposed to arsenic" Toxicology and Applied Pharmacology. 259:187–194

Published: March 2012
30. Hossain S, Kader G, Nikkon F, Yeasmin T "Hossain S, Kader G, Nikkon F, Yeasmin T. Cytotoxicity of the rhizome of medicinal plants," Asian Pac J Trop Biomed. 2:125–127

Published: February 2012
31. Yeasmin T, Kader G, Hossain S, Pervin R , Nikkon F "Yeasmin T, Kader G, Hossain S, Pervin R , Nikkon F. Nutritional values of lesser utilized aromatic medicinal plants" International research journal of pharmacy. 2:76-79

Published: January 2011

BMB-501 (Advanced Molecular Biology)

Description Not Provided

Running

BMB-401 (Molecular Biology and Genetic Engineering)

Description Not Provided

Running

PESS-1103 (Introductory Anatomy and Physiology)

Part-time Teaching, Department of Physical Education and Sports Science

BMIC-402 (Molecular Biology)

Part time teaching, Department of Microbiology

PESS-1205 ( Anatomy and Physiology of Organ System)

Part-time teaching, Department of Physical Education and Sports Science

GEB-1207 (Fundamentals of Biochemistry)

Part-time teaching, Department of Genetic Engineering and Biotechnology

Running

PESS 1104 (Basic Nutrition)

Part-time Teaching, Department of Physical Education and Sports Science)

2022- 2024, Administrator, Rajshahi University Press, University of Rajshahi.

2013-2014, Assistant Proctor, University of Rajshahi.

Not Available