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drmrkarim1965@ru.ac.bd

Department of Biochemistry and Molecular Biology


DR. M. REZAUL KARIM [2]
PROFESSOR
Biochemistry & Molecular Biology

Education Summary  
M.Sc. (Raj), M.Ag. & PhD (Japan)
Research Interest  
study of bioactive (antidiabetic, antioxidative) principles from plant, Plant biotechnology (crop protection and nutritional improvement), Nutritional Biochemistry and Food Technology
Level Institution Year
Doctoral
(PhD)		 Kagoshima University, Japan 2002
Masters
(M. Sc.Ag)		 Kagoshima University, Japan 1999
Masters
(M. Sc.)		 Rajshahi University 1986
Bachelor/Honors
(B. Sc. Honours)		 Rajshahi University 1985
Higher Secondary
(Higher Secondary Certificate)		 Krishnagobindapur College 1982
Secondary
(Secondary School Certificate)		 Krishnagobindapur High School 1980

Experience in Rajshahi University

Duration Organization/Institute Position
2007-08-28 to Biochemistry & Molecular Biology PROFESSOR
2002-05-18 to 2007-08-27 Biochemistry & Molecular Biology Associate Professor
1994-09-26 to 2002-05-17 Biochemistry & Molecular Biology ASSISTANT PROFESSOR
1991-09-26 to 1994-09-25 Biochemistry & Molecular Biology LECTURER

Experience in other Organization/Institute

Duration Organization/Institute Position
2011-01-11 to 2015-01-10 Dept. of Industrial Biotechnology, University Malaysia Pahang Contract Associate Professor
2009-10-01 to 2010-09-30 Faculty of Food Science and Technology, University Putra Malaysia, Selangor, Malaysia. PostDoc Fellow

Journal

1. Kh Nur E Sadid, Md. Anowar Hossain, Arifur Rahman Munshi, Md. Rezaul Karim "First Detection, Isolation and Molecular Characterization of Banana Leaf Spot Diseases Caused by Nigrospora sphaerica and Neocordana musae in Bangladesh." Archives of Phytopathology and Plant Protection (Vol. 56 Issue 14:1112-1125.

Published: October 2023

External Link
2. Md. Sajjad Hossen, Omar Nasib, Md. Tofazzal Hossain, Md. Rezaul Karim "Field Survey and Molecular Characterization of A Bipartite Begomovirus Causing Okra Yellow Vein Mosaic Virus Disease in the Rajshahi Region of Bangladesh." Indian Phytopathology

Published: October 2023

External Link
3. Md. Abdul Wadood, Md. Rezaul Karim, Sheikh Md. Abu Hena Mostafa Alim, Md. Masud Rana and Md. Golam Hossain "Factors affecting depression among married adults: a gender-based household crosssectional study" BMC Public Health 23:2077

Published: October 2023

External Link
4. K. Hasnin, M.M.Haque, M.M.U.Rashid, M.R. Karim and M.G. Hossain "Effect of socio-demographic, behavioral, biochemical factors and knowledge regarding diabetes on glycemic control among type 2 diabetes patients: A hospital based cross-sectional study" Human Biology Review 10(3): 265-281

Published: July 2021

External Link
5. Md. Abdul Wadood, Md. Rezaul Karim, Abdullah Al Mamun Hussain, Md. Masud Rana, Md. Golam Hossain "Bipolar disorder and self-perceived interpersonal relationships in the family: A household cross-sectional study among married adults in Rajshahi city, Bangladesh" Journal of Affective Disorders Reports, 5: 100169-100176

Published: July 2021

External Link
6. Md. Anowar Hossain, Arifur Rahman Munshi, Md. Sajjad Hossen, Kazi Zahidur Rahman, Md. Rezaul Karim, Yoshinobu Kimura "Morpho-molecular characterization of causative agents of wilting, leaf spot, fruit blight and stem canker of okra (Abelmoschus esculentus L.)" Archives of Phytopathology and Plant Protection, DOI: 10.1080/03235408.2021.1917283

Published: May 2021

External Link
7. Abdul Wadood, Rezaul Karim, Abdullah Al Mamun Hussain, Masud Rana, Golam Hossain "Risk factors of suicidality among married adults: A cross-sectional survey in Rajshahi City, Bangladesh" PLOS One, DOI:10.1371/journal.pone.0251717

Published: May 2021

External Link
8. M.A. Wadood, A.S.M.A. Mamun, M.R. Karim and M.G. Hossain "Co-occurrence of anemia among mother (15-49 years) and child (6-59 months) pairs: a cross-sectional study based on Bangladesh Health and Demographic Survey 2011" Human Biology Review; 10 (2), 200-217.

Published: April 2021

External Link
9. Aanada H. Jahurul, Chan Y. Ru, Ridhwan Norazlina, Mamat Hasmadi, Md Shaarani Sharifudin, Matanjun Patricia, Jau Shya Lee, Awal Shihabul Amir, H.M. Shariff, Jumardi Roslan, Noorakmar Ab Wahab, Rezaul Karim "Physicochemical properties of mango kernel fats extracted from different mango varieties cultivated in Sabah, Malaysia" Journal of Food Processing and Preservation, xx:xxx-xy

Published: July 2020

External Link
10. Md. Anowar Hossain, Md. Sajjad Hossain, Md. Arifur Rahman Munshi, Md. Rezaul Karim, Yoshinobu Kimura "Evaluation of the field performance and genetic diversity of 23 varieties of okra from Bangladesh using RAPD markers" Bangladesh Journal of Plant Taxonomy, 27(1):195-199

Published: June 2020

External Link
11. Wadood M.A, Karim M.R, Hussain AAM, Rana M.M, Hossain M.G "Bipolar disorder among married women in Bangladesh: Survey in Rajshahi city" PloSONE 15 (2)

Published: February 2020

External Link
12. Md. Anowar Hossain, Md. Sajjad Hossain, Md. Rezaul Karrim "Molecular Markers: Indispensable Tools for Genetic Diversity Analysis and Crop Improvement Biotechnology" International Journal of Plant Breeding and Crop Science,7(1): 613-623

Published: January 2020

External Link
13. M. A. Wadood, M. R. Karim, A. A. M. Hussain, M. M. Rana, M. M. Hasan, M. G. Hossain "Factors associated with bipolar disorder among married adult males in Rajshahi city, Bangladesh: A household study" Human Biology Review, 9 (1):88-102

Published: January 2020

External Link
14. Tan Suat Hian, Md. Rezaul Karim "Effects of three drying treatments on the polyphenol content, antioxidant and antimicrobial properties of Syzygium aromaticum extract" Chiang Mai Journal of Science 45(2):937-948

Published: March 2018

External Link
15. M. A. Hossain, H. A. Roslan, M. R. Karim, Y. Kimura "Molecular phylogeny, 3D-structural insights, docking and mechanisms of action of plant beta-galactosidases" International Journal of Bioinformatics Research and Applications, 12(2):149-179. DOI: 10.1504/IJBRA.2016.077125.

Published: January 2016

External Link
16. A. C. Mmurugan, D. Vallal, M. R. Karim, N. Govindan, M. M. Yusoff and M. M. Rahman "In vitro antiradical and neuroprotective activity of polyphenolic extract from marine algae Padina australis H." Journal of Chemical and Pharmaceutical Research, 7(8):355-362.

Published: October 2015

External Link
17. Asaduzzaman M., Sohanur Rahman M., Munira S., Muedur Rahman M., Hasan M., Siddique M.A.H., Biswas S., Belal M.H., Khatun M., Khan M.M.H., Rahman M.M., Karim M.R. and Islam M.A. "Effects of Honey Supplementation on Hepatic and Cardiovascular Disease (CVD) Marker in Streptozotocin-Induced Diabetic Rats" Journal of Diabetes & Metabolism, 6: 9-15.

Published: August 2015

External Link
18. M.S. Rahman, M. Asaduzzaman, S. Munira, H. Belal, M.M. Rahman, M. Hasan, S. Biswas, M.H. Khan, M. Rahman, M.R. Karim, M.A. Islam "Effects of Coccinia cordifolia (cucurbitaceae) leaves extract on hepatic and cardiovascular disease (cvd) markers in streptozotocin induced diabetic albino rats." International Journal of Pharmacy & Technology, 7(2): 9178-9189.

Published: July 2015

External Link
19. H.A. Hamid, M.M. Yusoff, M. Liu, M.R. Karim "α-Glucosidase and α-amylase inhibitory constituents of Tinospora crispa: Isolation and chemical profile confirmation by ultra-high performance liquid chromatography-quadrupole time-of-flight/mass spectrometry" Journal of functional foods 16: 74–80.

Published: June 2015

External Link
20. Mohammad A. Islam, Sohel Hasan, S. Munira, M Sohanur Rahman, M. Asaduzzaman, M. Muedur Rahman, M Khatun, M.H Khan, Ziaul Amin, Md Rezaul Karim-2, and Matiar Rahman "Inhibition of phospholipase A2 expression by the trans, trans conjugated linoleic acid isomers in mammary tumorigenesis induced by N-methyl-N-nitrosourea in Sprague Dawley Rat" Journal of Pharmacy and Biological Sciences,10 (3): 71-79

Published: May 2015
21. Shaheen M. Sarkar, M. Eaqub Ali, M. Shaharul Islam, M.Lutfor Rahman, S.S. Rashid, M. R. Karim and Mashitah M. Yusoff "Mesoporous silica-supported sulfonyldiamine ligand for microwave-assisted transfer hydrogenation" Journal of Nanomaterials, http://dx.doi.org/10.1155/2015/674752

Published: January 2015

External Link
22. A. C. Murugan, M. R. Karim, M. B. Mohd Yusoff, S. H. Tan, M. F. B. Farida Asras, and S. S. Rashid "New insights into seaweed polyphenols on glucose homeostasis." Informa Healthcare USA, Inc. 53(8):1087-97. doi: 10.3109/13880209.2014.959615

Published: January 2015

External Link
23. S. H. Tan, S. A. Manap, M. R. Karim, S. S. Rashid, M. Mahmood, N. L. Ma "Comparative flower pigment study of orchid plants" Advances in Environmental Biology, 8(20) S: 20-24.

Published: December 2014

External Link
24. M.R. Karim, M.S. Islam, Shaheen M. Sarkar, A.C. Murugan, Essam A. Makky, S.S. Rashid, Mashitah M. Yusoff "Anti-amylolytic activity of fresh and cooked okra (Hibiscus esculentus L.) pod extract." Biocatalysis and Agricultural Biotechnology. 3 (4), 373-377

Published: October 2014

External Link
25. Essam A. Makky, Y. C. Loh, M. R. Karim "Purification and partial characterization of a low molecular weight L-asparaginase produced from corn cob waste" Biocatalysis and Agricultural Biotechnology. DOI: 10.1016/j.bcab.2014.07.004

Published: October 2014

External Link
26. Essam A. Makky, Y. C. Loh, M. R. Karim "Purification and partial characterization of a low molecular weight l-asparaginase produced from corn cob waste" Biocatalysis and Agricultural Biotechnology. 3 (4):265-270 DOI: 10.1016/j.bcab.2014.07.004

Published: October 2014

External Link
27. I. S. M. Rafiqul, A. M. M. Sakinah, and M. R. Karim "Production of xylose from meranti wood sawdust by dilute acid hydrolysis." Appl Biochem Biotechnol. 174:542–555.

Published: September 2014

External Link
28. N. Hindryawati, G. P. Maniam, M. R. Karim, K. F. Chong "Transesterification of used cooking oil over alkali metal (Li, Na, K) supported rice husk silica as potential solid base catalyst" Engineering Science and Technology, an International Journal, 17: 95-103.

Published: June 2014

External Link
29. M. Z. Abedin, A. A Karim, A. A Latiff, C.-Y. Gan, F. C. Ghazali, Z. Barzideh, S. Ferdosh, M. J. H. Akanda, Wahiduzzaman, M. R. Karim, M. Z. I. Sarker "Biochemical and radical-scavenging properties of sea cucumber (Stichopus vastus) collagen hydrolysates" Natural Product Research. PMID: 24670209.

Published: March 2014

External Link
30. M.G .Sarowar Jahan, S. Pervin, A.Y.K.M. Masud Rana, M. S. Shovon, S.C. Dev Sharma, M. R. Karim, M. H. Rahman "Correlation between -amylase activity and starch content in different cultivars of radish (Raphanussativus L.)" BioTechnology: An Indian Journal. 9(7):298-302.

Published: January 2014

External Link
31. M. A. Rrashid, M. O. Faruque, Mahmuda Haque, M. R. Karim "Association of amylin in the development of impaired fasting glucose and impaired glucose tolerance." International Journal of Nutrition, Pharmacology, Neurological Diseases, 3(4):347-351.

Published: October 2013

External Link
32. S. Khatun, M. Ashraduzzaman, M. R.Karim, F. Pervin, N. Absar, and A. Rosma "Purification and characterization of peroxidase from Moringaoleifera L. leaves" Bioresources, 7(3): 3237-3251.

Published: August 2012

External Link
33. S. Ferdosh, M. Z. I. Sarker, N. N. N. Abd Rahman, J. Selamat, M. R. Karim, T. Abdul Razak and M. O. Abd Kadira* "Fish oil recovery from viscera of Indian Mackerel (Rastrelliger kanagurta) by supercritical fluid: An optimization approach." Journal of the Chinese Chemical Society, 58(3):DOI: 10.1002/jccs.201100235

Published: June 2012

External Link
34. K. Islam, A. Haque, M. Rezaul Karim, A. Fajol, E. Hossain, K. A. Salam, N. Ali, Z. A. Saud, M. Rahman, Mashiur Rahman, M. R. Karim, P. Sultana, M. Hossain, A. Azim Akhand, A. Mandal, H. Miyataka, S. Himeno And K. Hossain "Dose-response relationship between arsenic exposure and the serum enzymes for liver function tests in the individuals exposed to arsenic: A cross sectional study in Bangladesh" Environmental Health, 10:64 Doi:10.1186/1476-069x-10-64.

Published: July 2011

External Link
35. M. R. Karim and F. Hashinaga "Possible role of carboxyl and imidazole groups in the catalysis of pummelo limonoid glucosyltransferase." Chinese Journal of Catalysis, 31(12):1445-1451.

Published: December 2010

External Link
36. 3. N. Ali, Md. A. Hoque, A. Haque, K. A. Salam, M. R. Karim, A. Rahman, K. Islam, Z. A. Saud, M. A. Khalek, A. A. Akhand, M. Hossain, A. Mandal, M. R. Karim, H. Miyataka, S. Himeno and K. Hossain "Association between arsenic exposure and plasma cholinesterase activity: a population based study in Bangladesh." Environmental Health, 9: 36, DOI:10.1186/1476-069X-9-36.

Published: July 2010

External Link
37. N. K. Sana*, S. Pervin, M. G. Sarowar Jahan, M. M. H. Khan, M. R. Karim, B. C. Sarkar, R. K. Shaha "Partial purification and characterization of Urease from germinating chickpea (Cicer Arietinum L.) seed." Research & Reviews in Biosciences, 3(1): 1-5.

Published: June 2009

External Link
38. M. A. Hoque, S. Hoque, M. R. Karim and N. Absar "Activities of protease, amylase and cellulose in ber (Zizypus mauritiana Lam.) at three different maturity levels." J. Bangladesh Soc. Agric. Sci Technol. 5(1&2): 23-26.

Published: December 2008
39. M. A. Hoque, K. A. Salam, S. Hoque, M. R. Karim and N. Absar "Physico-chemical properties of ber (Zizypus mauritiana Lam.) at three different maturity levels." J. Bangladesh Soc. Agric. Sci. Technol. 5 (3 & 4): 67-70.

Published: June 2008
40. A. S. M. Noman, M. A. Hoque, M. M. Haque, F. Pervin, M. R. Karim "Nutritional and antinutritional factors in Pachyrhizus erosus L. tuber." Food Chemistry 102(4):1112-1118.

Published: December 2007

External Link
41. A. Qadir, F. Hashinaga, and M. R. Karim "Effects of pre-storage treatment with ethanol and CO2 on onion dormancy." Journal of Bio-Science, 15: 55-62.

Published: August 2007

External Link
42. S. Khatun, M. Ashraduzzman, N. Absar, F. Pervin, M. Abbas Ali, L. Bari, M. R. Karim and P. Hassan "Purification and characterization of three galactose-specific lectins from Sajna (Moringa oleifera L.) leaves." Journal of the Chinese Chemical Society, 54: 357-364.

Published: April 2007

External Link
43. F. Pervin, M. M. Hossain, S. Khatun, S. P. Siddiqui, K A. Salam, M. R. Karim and N. Absar "Comparative cytotoxicity study of six bioactive lectins purified from pondweed (Potamogeton nodosus Poir) rootstock on brine shrimp." Journal of Medical Sciences, 6(6): 999-1002.

Published: November 2006
44. A. S. M. Noman, M. A. Hoque, P. K. Sen and M. R. Karim "Purification and some properties of α–amylase from post-harvest Pachyrhizus errosus L. tuber." Food Chemistry, 99(3): 444-449.

Published: September 2006

External Link
45. M.I.I.E. Khuda, M.E. Haque, Lutfunnesa Bari, M.M. Parvin, M.Z. Rahman, K.M.K.B. Ferdaus and M. R. Karim "Seasonal variation in antibacterial activity of Bangladeshi honey against five pathogenic bacteria." Bangladesh J. Genet. Biotechnol. 6(1&2): 55-58.

Published: April 2005
46. M. R. Karim and F. Hashinaga "Preparation and properties of immobilized pummelo limonoid glucosyltransferase." Process Biochemistry, 38 (5): 809-814.

Published: December 2002

External Link
47. M. R. Karim and F. Hashinaga "Isolation and characterization of limonoid glucosyltransferase from pummelo albedo tissue." Food Chemistry, 76 (4): 431-436.

Published: April 2002

External Link
48. M. R. Karim and F. Hashinaga "Screening and some properties of limonoid glucosyltransferase from selected citrus varieties." Pakistan Journal of Biological Sciences, 4 (4): 483-486.

Published: December 2001
49. M. Z. Rahman, Z. A. Saud, N. Absar, M. R. Karim and F. Hashinaga "A comparative analysis on the purification and characterization of amylase from the flesh of healthy and disease-affected Moringa fruit (Moringa oleifera Lam)" Pakistan Journal of Biological Science, 3 (4): 586-589.

Published: December 2000
50. M. A. Razzaque, Z. A. Saud, N. Absar, M. R. Karim and F. Hashinaga "Purification and characterization of polyphenoloxidase from Guava infected with fruit-rot disease." Pakistan Journal of Biological Science, 3 (3): 407-410.

Published: September 2000
51. M.R. Karim, M.A. Islam, N. Absar and F. Hashinaga "Purification and partial characterization of a protease from tomato (Lycopersicon esculentum Mill)." Pakistan Journal of Biological Science, 2 (3): 955-959.

Published: September 1999
52. M. A. Hoque, N. Absar, M. R. Karim and P. Hassan "Purification and characterization of amylase from Ber (Zizypus mauritiana Lam) flesh of local-3 variety at mature stage." Journal of Biological Sciences, 6: 41-50.

Published: June 1998
53. N. Absar, K. K. Biswas and M. R. Karim "Purification and characterization of Rape seed (Brassica campestris L.) glycoproteins." Rajshahi University Studies Part-B, Journal of Science, 23-24: 53-62.

Published: June 1996
54. M. R. Karim, M. A. Islam, P. K. Sardar, M. A. Hossain and N. Absar "Activities of amylase, cellulase and protease in four varieties of tomato (Lycopersicon esculentum Mill) at different maturity levels." Bangladesh Journal of Life Science, 7 (1&2): 1-7.

Published: August 1995

Patent

1. Z. I. Sarker, J. Selamat, S. Ferdosh, M. R. Karim, "A process for fractionating polyunsaturated fatty acid-rich oil from a marine animal source." Malaysian patent (PI 2010002730).

Published: June 2010

External Link

Biochemistry of Natural Products

This course is offered to Postgraduate students in Biochemistry. The outlines of this course include definition, classification, sources, properties of secondary metabolites, their isolation, structure determination, biosynthesis, industrial production, m

Running

Clinical Biochemistry

This course is offered to undergraduate students (3rd year) in Biochemistry to develop skills in diagnostics and ability to explain the probable causes of the abnormality detected by clinical tests, make them aware of the safety measures to be taken in di

Running

Enzyme Technology

This course is offered to undergraduate students of the department of Industrial Biotechnology, UMP. The course deals with the introduction to enzymes, its kinetic study and application in different industries. Also the modification of enzymes for new fun

Bioanalytical Chemistry

This course is offered to undergraduate students of the department of Industrial Biotechnology, UMP. This course introduces spectroscopic methods for matrix characterization, principles of electrophoresis, isoelectric focusing, capillary electrophoresis,

Basic Biochemistry (BMB101)

This course is offered to provide the students with basic knowledge on the scopes and prospects of Biochemistry, its relation with other branches of Bioscience, concept of Basic biomolecules of life, their structure-function relationship, biological role,

Running

Supervisory Experience (Undergraduate  to PhD):

The following students graduated under my supervision in M. Phil or PhD:

i) Md. Touhidul Islam, “Promoting the usage of underutilized crops and fruits in Bangladesh”, PhD student enrolled in July 2003, Degree awarded in September, 2008.

ii) Kaniz Hasnin, “Socioanthropometric and biochemical characterization of diabetic patients in Rajshahi area: a hospital based study”. PhD student enrolled in July 2003, Degree awarded in 2012. 

iii) Mrs Kuhilika Akhter, “Determinants of hyper-homocysteinemia in type-2 diabetic subjects”, M. Phil student enrolled in July, 2007, Degree completed in 2013. 

iv) Md. Abdul Wadud, MBBS, “Household study on dual burden of bipolar disorder among couples of Rajshahi city in Bangladesh”, M. Phil student enrolled in July, 2016, to be completed soon.

v) Md. Suzon Al Hasan, MBBS, FCPS, (Physical Medicine) “Factors associated with porosity of bone among women of Rajshahi city”

vi) Kazi Zahidur Rahman “Development of nutritionally improved okra variety by mutation breeding for the resistance against viral resistance” PhD student enrolled in July 2015, to be completed soon

vii) More than 15 Master students have graduated under my supervision.

viii) More than 20 Undergraduate students have graduated under my supervision.

Reviewer of International Journals:

i) Critical Reviews of Food Science and Food Safety

ii) Journal of Pesticide Biochemistry and Physiology

iii) Food Chemistry

iv) Process Biochemistry

v) Journal of Environmental Biology

vi) African Journal of Biotechnology

vii) Food Reviews International

viii) International Journal of Food Properties

ix) Journal of Bio ScienceJournal


  • BMB-307 (Clinical Biochemistry)
    • Lesson Plan
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    • Lecture-1 (Metabolites as diagnostic tools)
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    • Lecture-2 (Electrolytes as clinical tools)
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    • Lecture-3 (Genetic disorders and their diagnosis)
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    • Lecture-5 (Genetic disorders and their diagnosis)
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    • Lecture-6 (Genetic disorders and their diagnosis)
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    • Lecture-7 (Genetic disorders and their diagnosis)
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    • Lecture-8 (Multifactorial diseases and their management)
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    • Lecture-9 (Multifactorial diseases and their management)
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    • Lecture-10 (Diseases of the muscle and their investigation)
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  • BMB-507 (Biochemistry of Natural Products
    • Lesson Plan
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    • Lecture-1 (Terpenoid biosynthesis: Biosynthesis of IPP)
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    • Lecture-2 (Biosynthesis of Phenolic compounds)
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    • Lecture-3 (Flavonoid biosynthesis)
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    • Lecture-4 (Industrial production of vitamin B-12 and vitamin E)
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    • Lecture-5 (Production of steroid hormone and vitamin D)
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    • Lecture- 6 (Current approaches toward production of secondary plant metabolites:Rationale)
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    • Lecture-7-9 (Production of secondary metabolite from medicinal plant by tissue and organ culture)
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  • BMB-101 (Basic Biochemistry)